UCLA Brain Mapping Center

Publications

Three-dimensional mapping of hippocampal anatomy in adolescents with bipolar disorder.

Bearden CE; Soares JC; Klunder AD; Nicoletti M; Dierschke N; Hayashi KM; Narr KL; Brambilla P; Sassi RB; Axelson D; Ryan N; Birmaher B; Thompson PM;
Journal of the American Academy of Child and Adolescent Psychiatry. 2008-May; 47(515-25):5
 
Early-onset bipolar disorder is thought to be a particularly severe variant of the illness. Continuity with the adult form of illness remains unresolved, but preliminary evidence suggests similar biological underpinnings. Recently, we observed localized hippocampal decreases in unmedicated adults with bipolar disorder that were not detectable with conventional volumetric measures. Using the same three-dimensional mapping methods, we sought to investigate whether a similar pattern exists in adolescents with bipolar disorder.
 
PMID: 18356767    doi: 10.1097/CHI.0b013e31816765ab
 

BMAP Author