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Cerebral glucose metabolic rates in nondepressed patients with obsessive-compulsive disorder.
Baxter LR; Schwartz JM; Mazziotta JC; Phelps ME; Pahl JJ; Guze BH; Fairbanks L; The American journal of psychiatry. 1988-Dec; 145(1560-3):12
The authors compared 10 nondepressed patients with obsessive-compulsive disorder with 10 normal control subjects of the same sex and similar age for cerebral glucose metabolic rates obtained using positron emission tomography. Obsessive-compulsive patients showed significantly elevated metabolic rates in the whole cerebral hemispheres, heads of the caudate nuclei, orbital gyri, and the orbital gyri relative to the ipsilateral hemisphere (the orbital-hemisphere ratio). These results are similar to those the authors reported previously for another group of obsessive-compulsive patients and normal control subjects.
PMID:
3264118 doi:
10.1038/jcbfm.1989.68
BMAP Author
John Mazziotta M.D., Ph.D.
310-825-2699